4HDQ

Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail

4HDQ の概要

• エントリーDOI: 10.2210/pdb4hdq/pdb
• 関連するPDBエントリー: 4HDO
• 分子名称: Krev interaction trapped protein 1, Ras-related protein Rap-1b, Protein HEG homolog 1, ... (7 entities in total)
• 機能のキーワード: ra binding motif, gtpase, heg1 cytoplasmic tail, ptd domain, rap1 effector, transmembrane protein, rap1, heg1, cell-cell junctions, plasma membrane, nucleus, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: O00522; Cell membrane: P61224; Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Isoform 2: Secreted (Potential): Q9ULI3
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 60201.91

構造登録者

Gingras, A.R. (登録日: 2012-10-02, 公開日: 2013-07-10, 最終更新日: 2023-09-20)

• 主引用文献: Gingras, A.R.,Puzon-McLaughlin, W.,Ginsberg, M.H.; The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.; J.Biol.Chem., 288:23639-23649, 2013; PubMed: 23814056; DOI: 10.1074/jbc.M113.462911

実験手法

X-RAY DIFFRACTION (1.95 Å)