4HC7

Crystal structure of the full DNA binding domain of GATA3-complex 2

Summary for 4HC7

• Entry DOI: 10.2210/pdb4hc7/pdb
• Related: 4HC9 4HCA
• Descriptor: Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ... (5 entities in total)
• Functional Keywords: gata transcription factor, zinc finger, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P23771
• Total number of polymer chains: 6
• Total formula weight: 50579.37

Authors

Chen, Y.,Bates, D.L.,Dey, R.,Chen, L. (deposition date: 2012-09-28, release date: 2012-12-05, Last modification date: 2024-02-28)

• Primary citation: Chen, Y.,Bates, D.L.,Dey, R.,Chen, P.H.,Machado, A.C.,Laird-Offringa, I.A.,Rohs, R.,Chen, L.; DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.; Cell Rep, 2:1197-1206, 2012; PubMed: 23142663; DOI: 10.1016/j.celrep.2012.10.012

Experimental method

X-RAY DIFFRACTION (2.65 Å)