4HAF

Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form)

4HAF の概要

• エントリーDOI: 10.2210/pdb4haf/pdb
• 関連するPDBエントリー: 3ave 4HAG
• 分子名称: Ig gamma-2 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: immunoglobulin fold, immune system
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P01859
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51688.29

構造登録者

Teplyakov, A.,Malia, T.,Obmolova, G.,Zhao, Y.,Gilliland, G. (登録日: 2012-09-26, 公開日: 2013-06-12, 最終更新日: 2023-09-20)

• 主引用文献: Teplyakov, A.,Zhao, Y.,Malia, T.J.,Obmolova, G.,Gilliland, G.L.; IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface.; Mol.Immunol., 56:131-139, 2013; PubMed: 23628091; DOI: 10.1016/j.molimm.2013.03.018

実験手法

X-RAY DIFFRACTION (2.04 Å)