4H67
Crystal structure of HMP synthase Thi5 from S. cerevisiae
Summary for 4H67
Entry DOI | 10.2210/pdb4h67/pdb |
Related | 4H65 4H6D |
Descriptor | Pyrimidine precursor biosynthesis enzyme THI5, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total) |
Functional Keywords | hmp-p synthase, thi5-plp complex, plp binding, transferase |
Biological source | Saccharomyces cerevisiae (yeast) |
Total number of polymer chains | 8 |
Total formula weight | 316515.15 |
Authors | Coquille, S.C.,Roux, C.,Fitzpatrick, T.,Thore, S. (deposition date: 2012-09-19, release date: 2012-10-17, Last modification date: 2023-09-20) |
Primary citation | Coquille, S.,Roux, C.,Fitzpatrick, T.B.,Thore, S. The Last Piece in the Vitamin B1 Biosynthesis Puzzle: STRUCTURAL AND FUNCTIONAL INSIGHT INTO YEAST 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE (HMP-P) SYNTHASE. J.Biol.Chem., 287:42333-42343, 2012 Cited by PubMed: 23048037DOI: 10.1074/jbc.M112.397240 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report