4H65
Crystal structure of SeMet derivative of HMP synthase Thi5 from S. cerevisiae
Summary for 4H65
| Entry DOI | 10.2210/pdb4h65/pdb |
| Related | 4H67 4H6D |
| Descriptor | Pyrimidine precursor biosynthesis enzyme THI5 (2 entities in total) |
| Functional Keywords | hmp-p synthase, thi5-plp complex, plp binding, transferase |
| Biological source | Saccharomyces cerevisiae (yeast) |
| Total number of polymer chains | 2 |
| Total formula weight | 79502.84 |
| Authors | Coquille, S.C.,Roux, C.,Fitzpatrick, T.,Thore, S. (deposition date: 2012-09-19, release date: 2012-10-17, Last modification date: 2013-01-23) |
| Primary citation | Coquille, S.,Roux, C.,Fitzpatrick, T.B.,Thore, S. The Last Piece in the Vitamin B1 Biosynthesis Puzzle: STRUCTURAL AND FUNCTIONAL INSIGHT INTO YEAST 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE (HMP-P) SYNTHASE. J.Biol.Chem., 287:42333-42343, 2012 Cited by PubMed: 23048037DOI: 10.1074/jbc.M112.397240 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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