4H4F

Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis

4H4F の概要

• エントリーDOI: 10.2210/pdb4h4f/pdb
• 分子名称: Chymotrypsin-C, Eglin C, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: serine protease, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 37441.99

構造登録者

Batra, J.,Soares, A.S.,Radisky, E.S. (登録日: 2012-09-17, 公開日: 2013-02-27, 最終更新日: 2013-04-24)

• 主引用文献: Batra, J.,Szabo, A.,Caulfield, T.R.,Soares, A.S.,Sahin-Toth, M.,Radisky, E.S.; Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation.; J.Biol.Chem., 288:9848-9859, 2013; PubMed: 23430245; DOI: 10.1074/jbc.M113.457382

実験手法

X-RAY DIFFRACTION (1.9 Å)