4H4B
Human cytosolic 5'-nucleotidase II in complex with Anthraquinone-2,6- disulfonic acid
Summary for 4H4B
| Entry DOI | 10.2210/pdb4h4b/pdb |
| Related | 2J2C 2XCX |
| Descriptor | Cytosolic purine 5'-nucleotidase, 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | high km 5-prime nucleotidase, cn-ii, nucleotide-binding, phosphoprotein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P49902 |
| Total number of polymer chains | 1 |
| Total formula weight | 65053.98 |
| Authors | Rhimi, M.,Aghajari, N. (deposition date: 2012-09-17, release date: 2012-12-26, Last modification date: 2023-09-20) |
| Primary citation | Jordheim, L.P.,Marton, Z.,Rhimi, M.,Cros-Perrial, E.,Lionne, C.,Peyrottes, S.,Dumontet, C.,Aghajari, N.,Chaloin, L. Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening. Biochem Pharmacol, 85:497-506, 2013 Cited by PubMed: 23220537DOI: 10.1016/j.bcp.2012.11.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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