4H4B

Human cytosolic 5'-nucleotidase II in complex with Anthraquinone-2,6- disulfonic acid

4H4B の概要

• エントリーDOI: 10.2210/pdb4h4b/pdb
• 関連するPDBエントリー: 2J2C 2XCX
• 分子名称: Cytosolic purine 5'-nucleotidase, 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: high km 5-prime nucleotidase, cn-ii, nucleotide-binding, phosphoprotein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P49902
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65053.98

構造登録者

Rhimi, M.,Aghajari, N. (登録日: 2012-09-17, 公開日: 2012-12-26, 最終更新日: 2023-09-20)

• 主引用文献: Jordheim, L.P.,Marton, Z.,Rhimi, M.,Cros-Perrial, E.,Lionne, C.,Peyrottes, S.,Dumontet, C.,Aghajari, N.,Chaloin, L.; Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening.; Biochem Pharmacol, 85:497-506, 2013; PubMed: 23220537; DOI: 10.1016/j.bcp.2012.11.024

実験手法

X-RAY DIFFRACTION (2.9 Å)