4H1W
E1 structure of the (SR) Ca2+-ATPase in complex with Sarcolipin
Summary for 4H1W
Entry DOI | 10.2210/pdb4h1w/pdb |
Related | 1T5S 1T5T 2C8K 3B9B |
Descriptor | SERCA1a, Sarcolipin, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | p-type atpase, ca2+ transport, sarcolipin, phospholamban, membrane protein, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator |
Biological source | Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits) More |
Cellular location | Membrane ; Multi-pass membrane protein : B6CAM1 Sarcoplasmic reticulum membrane ; Single-pass membrane protein : P42532 |
Total number of polymer chains | 2 |
Total formula weight | 113996.34 |
Authors | Bublitz, M.,Winther, A.-M.L.,Karlsen, J.,Moller, J.V.,Hansen, J.B.,Buch-Pedersen, M.J.,Nissen, P. (deposition date: 2012-09-11, release date: 2013-03-06, Last modification date: 2024-02-28) |
Primary citation | Winther, A.M.,Bublitz, M.,Karlsen, J.L.,Moller, J.V.,Hansen, J.B.,Nissen, P.,Buch-Pedersen, M.J. The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. Nature, 495:265-269, 2013 Cited by PubMed: 23455424DOI: 10.1038/nature11900 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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