4H10

Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA

Summary for 4H10

DescriptorAryl hydrocarbon receptor nuclear translocator-like protein 1, Circadian locomoter output cycles protein kaput, E-box DNA sense strand, ... (5 entities in total)
Functional Keywordsbhlh, circadian transcription, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (By similarity) O00327
Nucleus O15516
Total number of polymer chains4
Total molecular weight26409.05
Authors
Wang, Z.,Su, X.-D. (deposition date: 2012-09-10, release date: 2012-12-26, Last modification date: 2013-02-20)
Primary citation
Wang, Z.,Wu, Y.,Li, L.,Su, X.D.
Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
Cell Res., 23:213-224, 2013
PubMed: 23229515 (PDB entries with the same primary citation)
DOI: 10.1038/cr.2012.170
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.402 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.237220.8%12.0%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4h10
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Molmil generated image of 4h10
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Molmil generated image of 4h10
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