4H0D

New Delhi Metallo-beta-Lactamase-1 Complexed with Mn from Klebsiella pneumoniae

Summary for 4H0D

Entry DOI	10.2210/pdb4h0d/pdb
Related	3RKJ 3RKK 3SBL 3SFP 3SRX 4GYQ 4GYU
Descriptor	Beta-lactamase NDM-1, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, MANGANESE (II) ION, ... (9 entities in total)
Functional Keywords	structural genomics, psi-biology, midwest center for structural genomics, mcsg, structures of mtb proteins conferring susceptibility to known mtb inhibitors, mtbi, alpha-beta-beta-alpha fold, hydrolase, hydrolase-antibiotics complex, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological source	Klebsiella pneumoniae
Cellular location	Periplasm (Potential): C7C422
Total number of polymer chains	2
Total formula weight	52764.60
Authors	Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Binkowski, T.A.,Mire, J.,Sacchettini, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (deposition date: 2012-09-07, release date: 2012-09-26, Last modification date: 2024-02-28)
Primary citation	Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Binkowski, T.A.,Mire, J.,Sacchettini, J.,Joachimiak, A. New Delhi Metallo-beta-Lactamase-1 Complexed with Mn from Klebsiella pneumoniae To be Published,
Experimental method	X-RAY DIFFRACTION (1.498 Å)

Structure validation