4GZR

Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221

Summary for 4GZR

• Entry DOI: 10.2210/pdb4gzr/pdb
• Related: 3OGI
• Descriptor: ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION, ... (4 entities in total)
• Functional Keywords: wxg100, structural genomics, tb structural genomics consortium, tbsgc, integrated center for structure and function innovation, isfi, unknown function, secreted, psi-2, protein structure initiative
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 4
• Total formula weight: 44028.50

Authors

Arbing, M.A.,Chan, S.,He, Q.,Harris, L.,Zhou, T.T.,Kuo, E.,Ahn, C.J.,Eisenberg, D.,TB Structural Genomics Consortium (TBSGC),Integrated Center for Structure and Function Innovation (ISFI) (deposition date: 2012-09-06, release date: 2012-09-26, Last modification date: 2023-09-13)

• Primary citation: Arbing, M.A.,Chan, S.,Harris, L.,Kuo, E.,Zhou, T.T.,Ahn, C.J.,Nguyen, L.,He, Q.,Lu, J.,Menchavez, P.T.,Shin, A.,Holton, T.,Sawaya, M.R.,Cascio, D.,Eisenberg, D.; Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.; Plos One, 8:e81753-e81753, 2013; PubMed: 24312350; DOI: 10.1371/journal.pone.0081753

Experimental method

X-RAY DIFFRACTION (2.553 Å)