4GZ6
Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc
Summary for 4GZ6
Entry DOI | 10.2210/pdb4gz6/pdb |
Related | 4GYW 4GYY 4GZ3 4GZ5 |
Descriptor | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ogt, o-glcnac, gt-b, glycosyltransferase, o-glcnacylation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Mitochondrion. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm: O15294 |
Total number of polymer chains | 4 |
Total formula weight | 328024.78 |
Authors | Lazarus, M.B.,Jiang, J.,Gloster, T.M.,Zandberg, W.F.,Vocadlo, D.J.,Walker, S. (deposition date: 2012-09-06, release date: 2012-10-31, Last modification date: 2024-02-28) |
Primary citation | Lazarus, M.B.,Jiang, J.,Gloster, T.M.,Zandberg, W.F.,Whitworth, G.E.,Vocadlo, D.J.,Walker, S. Structural snapshots of the reaction coordinate for O-GlcNAc transferase. Nat.Chem.Biol., 8:966-968, 2012 Cited by PubMed: 23103939DOI: 10.1038/nchembio.1109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.98 Å) |
Structure validation
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