4GZ1
Mus Musculus Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex at 1.5 Angstroms resolution
Summary for 4GZ1
Entry DOI | 10.2210/pdb4gz1/pdb |
Related | 4GYZ 4GZ0 4GZ2 |
Descriptor | Tyrosyl-DNA phosphodiesterase 2, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total) |
Functional Keywords | protein-dna complex, dna repair, 5'-dna end processing, endonuclease/exonuclease/phosphatase domain, eep domain, 5'-dna end recognition, hydrolase-dna complex, hydrolase/dna |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 63544.85 |
Authors | Schellenberg, M.J.,Williams, R.S. (deposition date: 2012-09-05, release date: 2012-10-31, Last modification date: 2024-02-28) |
Primary citation | Schellenberg, M.J.,Appel, C.D.,Adhikari, S.,Robertson, P.D.,Ramsden, D.A.,Williams, R.S. Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. Nat.Struct.Mol.Biol., 19:1363-1371, 2012 Cited by PubMed: 23104055DOI: 10.1038/nsmb.2418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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