4GY5

Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3

4GY5 の概要

• エントリーDOI: 10.2210/pdb4gy5/pdb
• 分子名称: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION, ... (4 entities in total)
• 機能のキーワード: histone binding, ligase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: Q96T88 P84243
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 115359.35

構造登録者

Cheng, J.,Yang, Y.,Fang, J.,Xiao, J.,Zhu, T.,Chen, F.,Wang, P.,Xu, Y. (登録日: 2012-09-05, 公開日: 2012-11-14, 最終更新日: 2023-11-08)

• 主引用文献: Cheng, J.,Yang, Y.,Fang, J.,Xiao, J.,Zhu, T.,Chen, F.,Wang, P.,Li, Z.,Yang, H.,Xu, Y.; Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein; J.Biol.Chem., 288:1329-1339, 2013; PubMed: 23161542; DOI: 10.1074/jbc.M112.415398

実験手法

X-RAY DIFFRACTION (2.956 Å)