4GWS
Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity
Summary for 4GWS
Entry DOI | 10.2210/pdb4gws/pdb |
Related | 4GWU 4GWW 4GWX 4GWY 4GWZ 4GX3 4GX4 4GX6 |
Descriptor | Fructose-1,6-bisphosphatase 1, 6-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | allosteric enzymes, amp inhibition, synergism, hydrolase |
Biological source | Sus scrofa (pig) |
Total number of polymer chains | 2 |
Total formula weight | 75150.03 |
Authors | Gao, Y.,Honzatko, R.B. (deposition date: 2012-09-03, release date: 2013-09-04, Last modification date: 2023-09-13) |
Primary citation | Gao, Y.,Shen, L.,Honzatko, R.B. Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fructose 2,6-bisphosphate Inhibition To be Published, |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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