4GWK

Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid

4GWK の概要

• エントリーDOI: 10.2210/pdb4gwk/pdb
• 関連するPDBエントリー: 2JKV 4GWG
• 分子名称: 6-phosphogluconate dehydrogenase, decarboxylating, 3-PHOSPHOGLYCERIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: 6-phosphogluconate dehydrogenase, 3-phosphoglycerate, dehydrogenase, nadp, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (By similarity): P52209
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54037.43

構造登録者

He, C.,Zhou, L.,Zhang, L. (登録日: 2012-09-03, 公開日: 2012-11-28, 最終更新日: 2023-09-13)

• 主引用文献: Hitosugi, T.,Zhou, L.,Elf, S.,Fan, J.,Kang, H.B.,Seo, J.H.,Shan, C.,Dai, Q.,Zhang, L.,Xie, J.,Gu, T.L.,Jin, P.,Aleckovic, M.,Leroy, G.,Kang, Y.,Sudderth, J.A.,Deberardinis, R.J.,Luan, C.H.,Chen, G.Z.,Muller, S.,Shin, D.M.,Owonikoko, T.K.,Lonial, S.,Arellano, M.L.,Khoury, H.J.,Khuri, F.R.,Lee, B.H.,Ye, K.,Boggon, T.J.,Kang, S.,He, C.,Chen, J.; Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.; Cancer Cell, 22:585-600, 2012; PubMed: 23153533; DOI: 10.1016/j.ccr.2012.09.020

実験手法

X-RAY DIFFRACTION (1.534 Å)