4GUJ

1.50 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) in Complex with Shikimate

4GUJ の概要

• エントリーDOI: 10.2210/pdb4guj/pdb
• 関連するPDBエントリー: 4GUF 4GUG 4GUH 4GUI
• 分子名称: 3-dehydroquinate dehydratase, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ZINC ION, ... (4 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, lyase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55803.83

構造登録者

Light, S.H.,Minasov, G.,Duban, M.-E.,Shuvalova, L.,Kwon, K.,Lavie, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2012-08-29, 公開日: 2012-09-12, 最終更新日: 2023-09-13)

• 主引用文献: Light, S.H.,Antanasijevic, A.,Krishna, S.N.,Caffrey, M.,Anderson, W.F.,Lavie, A.; Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of schiff base formation.; Biochemistry, 53:872-880, 2014; PubMed: 24437575; DOI: 10.1021/bi4015506

実験手法

X-RAY DIFFRACTION (1.5 Å)