4GUE
Structure of N-terminal kinase domain of RSK2 with flavonoid glycoside quercitrin
Summary for 4GUE
Entry DOI | 10.2210/pdb4gue/pdb |
Related | 3UBD 4EL9 |
Descriptor | Ribosomal protein S6 kinase alpha-3, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | serine/threonine kinase domain, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Mus musculus (mouse) |
Cellular location | Nucleus (By similarity): P18654 |
Total number of polymer chains | 1 |
Total formula weight | 35639.58 |
Authors | Derewenda, U.,Utepbergenov, D.,Szukalska, G.,Derewenda, Z.S. (deposition date: 2012-08-29, release date: 2013-01-30, Last modification date: 2023-09-13) |
Primary citation | Derewenda, U.,Artamonov, M.,Szukalska, G.,Utepbergenov, D.,Olekhnovich, N.,Parikh, H.I.,Kellogg, G.E.,Somlyo, A.V.,Derewenda, Z.S. Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution. Acta Crystallogr.,Sect.D, 69:266-275, 2013 Cited by PubMed: 23385462DOI: 10.1107/S0907444912045520 PDB entries with the same primary citation |
Experimental method |
Structure validation
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