4GRZ
Crystal structure of SHP1 catalytic domain with PO4
Summary for 4GRZ
Entry DOI | 10.2210/pdb4grz/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 6, PHOSPHATE ION (3 entities in total) |
Functional Keywords | phosphatase domain, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P29350 |
Total number of polymer chains | 1 |
Total formula weight | 33013.09 |
Authors | Alicea-Velazquez, N.L.,Jakoncic, J.,Boggon, T.J. (deposition date: 2012-08-27, release date: 2012-12-19, Last modification date: 2023-09-13) |
Primary citation | Alicea-Velazquez, N.L.,Jakoncic, J.,Boggon, T.J. Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition. J.Struct.Biol., 181:243-251, 2013 Cited by PubMed: 23296072DOI: 10.1016/j.jsb.2012.12.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3732 Å) |
Structure validation
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