4GOW

Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex

Summary for 4GOW

Entry DOI	10.2210/pdb4gow/pdb
Descriptor	Calmodulin, Potassium voltage-gated channel subfamily KQT member 4, CALCIUM ION, ... (4 entities in total)
Functional Keywords	protein complex, protein binding, ion channel, calmodulin, potassium channel
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, spindle: P62158 Basal cell membrane; Multi-pass membrane protein: P56696
Total number of polymer chains	2
Total formula weight	24706.91
Authors	Xu, Q.,Chang, A.,Tolia, A.,Minor Jr., D.L. (deposition date: 2012-08-20, release date: 2012-12-12, Last modification date: 2024-02-28)
Primary citation	Xu, Q.,Chang, A.,Tolia, A.,Minor, D.L. Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation. J.Mol.Biol., 425:378-394, 2013 Cited by PubMed: 23178170 DOI: 10.1016/j.jmb.2012.11.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation