4GMD

The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate

Summary for 4GMD

• Entry DOI: 10.2210/pdb4gmd/pdb
• Related: 4E5U 4EDH 4ESH
• Descriptor: Thymidylate kinase, 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: structural genomics, psi-biology, midwest center for structural genomics, mcsg, structures of mtb proteins conferring susceptibility to known mtb inhibitors, mtbi, protein structure initiative, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 4
• Total formula weight: 95552.36

Authors

Tan, K.,Joachimiak, G.,Jedrzejczak, R.,Sacchettini, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (deposition date: 2012-08-15, release date: 2012-08-29, Last modification date: 2023-09-13)

• Primary citation: Tan, K.,Joachimiak, G.,Jedrzejczak, R.,Sacchettini, J.,Joachimiak, A.; The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate; To be Published,

Experimental method

X-RAY DIFFRACTION (1.98 Å)