4GLP

The crystal structure of soluble human CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket.

Summary for 4GLP

Entry DOI	10.2210/pdb4glp/pdb
Descriptor	Monocyte differentiation antigen CD14 (1 entity in total)
Functional Keywords	alpha beta bent solenoid, lrr, lipopolysaccharide, serum, cd14, leucine-rich repeat, pattern recognition, endotoxin, sepsis, immune system
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Lipid- anchor, GPI-anchor : P08571
Total number of polymer chains	1
Total formula weight	33509.28
Authors	Kelley, S.L.,Lukk, T.,Nair, S.K.,Tapping, R.I. (deposition date: 2012-08-14, release date: 2012-12-26, Last modification date: 2021-05-26)
Primary citation	Kelley, S.L.,Lukk, T.,Nair, S.K.,Tapping, R.I. The Crystal Structure of Human Soluble CD14 Reveals a Bent Solenoid with a Hydrophobic Amino-Terminal Pocket. J.Immunol., 190:1304-1311, 2013 Cited by PubMed: 23264655 DOI: 10.4049/jimmunol.1202446 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.002 Å)

Structure validation