4GK8

Crystal structure of histidinol phosphate phosphatase (HISK) from Lactococcus lactis subsp. lactis Il1403 complexed with ZN and L-histidinol arsenate

Summary for 4GK8

• Entry DOI: 10.2210/pdb4gk8/pdb
• Related: 4GC3
• Descriptor: Histidinol-phosphatase, ZINC ION, {[(2S)-2-amino-3-(1H-imidazol-5-yl)propyl]oxy}(trihydroxy)-lambda~5~-arsanyl, ... (7 entities in total)
• Functional Keywords: php fold, hydrolase
• Biological source: Lactococcus lactis subsp. lactis
• Total number of polymer chains: 1
• Total formula weight: 34045.08

Authors

Fedorov, A.A.,Fedorov, E.V.,Ghodge, S.,Raushel, F.M.,Almo, S.C. (deposition date: 2012-08-10, release date: 2013-02-27, Last modification date: 2023-09-13)

• Primary citation: Ghodge, S.V.,Fedorov, A.A.,Fedorov, E.V.,Hillerich, B.,Seidel, R.,Almo, S.C.,Raushel, F.M.; Structural and Mechanistic Characterization of l-Histidinol Phosphate Phosphatase from the Polymerase and Histidinol Phosphatase Family of Proteins.; Biochemistry, 52:1101-1112, 2013; PubMed: 23327428; DOI: 10.1021/bi301496p

Experimental method

X-RAY DIFFRACTION (1.933 Å)