4GIY

tRNA Guanine Transglycosylase in complex with disubstituted lin-benzoguanine inhibitor

Summary for 4GIY

• Entry DOI: 10.2210/pdb4giy/pdb
• Related: 3EOS 4GH3 4GI1
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-[(2-phenylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• Functional Keywords: tim barrel, glycosyltransferase, queuosine, biosynthesis, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43450.70

Authors

Immekus, F.,Klebe, G. (deposition date: 2012-08-09, release date: 2013-09-04, Last modification date: 2023-09-13)

• Primary citation: Immekus, F.,Barandun, L.J.,Diederich, F.,Klebe, G.; Two-armed benzopurine inhibitors of TGT; To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)