4GIY

tRNA Guanine Transglycosylase in complex with disubstituted lin-benzoguanine inhibitor

4GIY の概要

• エントリーDOI: 10.2210/pdb4giy/pdb
• 関連するPDBエントリー: 3EOS 4GH3 4GI1
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-[(2-phenylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• 機能のキーワード: tim barrel, glycosyltransferase, queuosine, biosynthesis, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Zymomonas mobilis subsp. mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43450.70

構造登録者

Immekus, F.,Klebe, G. (登録日: 2012-08-09, 公開日: 2013-09-04, 最終更新日: 2023-09-13)

• 主引用文献: Immekus, F.,Barandun, L.J.,Diederich, F.,Klebe, G.; Two-armed benzopurine inhibitors of TGT; To be Published,

実験手法

X-RAY DIFFRACTION (1.75 Å)