4GIO

Crystal structure of Campylobacter jejuni cj0090

Summary for 4GIO

• Entry DOI: 10.2210/pdb4gio/pdb
• Descriptor: Putative lipoprotein, BROMIDE ION (3 entities in total)
• Functional Keywords: lipoprotein, unknown function
• Biological source: Campylobacter jejuni subsp. jejuni
• Total number of polymer chains: 2
• Total formula weight: 24853.77

Authors

Kawai, F.,Yeo, H.J. (deposition date: 2012-08-08, release date: 2012-09-26, Last modification date: 2024-02-28)

Primary citation

Paek, S.,Kawai, F.,Choi, K.J.,Yeo, H.J.
Crystal structure of the Campylobacter jejuni Cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins.
Proteins, 80:2804-2809, 2012

PubMed Abstract: Bacterial lipoproteins play an important role in bacterial pathogenesis and physiology. The genome of Campylobacter jejuni, a major foodborn pathogen, is predicted to contain over 20 lipoproteins. However, the functions of the majority of C. jejuni lipoproteins remain unknown. The Cj0090 protein is encoded by a lipoprotein operon composed of cj0089, cj0090, and cj0091. Here, we report the crystal structure of Cj0090 at 1.9 Å resolution, revealing a novel variant of the immunoglobulin fold with β-sandwich architecture. The structure suggests that Cj0090 may be involved in protein-protein interactions, consistent with a possible role for bacterial lipoproteins.

PubMed: 22987763
DOI: 10.1002/prot.24182

Experimental method

X-RAY DIFFRACTION (1.9 Å)