4GH4

Crystal Structure of Foot and Mouth Disease Virus A22 Serotype

4GH4 の概要

• エントリーDOI: 10.2210/pdb4gh4/pdb
• 関連するPDBエントリー: 1BBT 1FMD
• 分子名称: capsid protein VP1, capsid protein VP2, capsid protein VP3, ... (5 entities in total)
• 機能のキーワード: icosahedral virus, capsids, picornavirus, apthovirus, virus
• 由来する生物種: Foot-and-mouth disease virus - type A; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75510.98

構造登録者

Kotecha, A.,Jinshan, R.,Curry, S.,Fry, E.,Stuart, D. (登録日: 2012-08-07, 公開日: 2013-02-20, 最終更新日: 2024-02-28)

主引用文献

Curry, S.,Fry, E.,Blakemore, W.,Abu-Ghazaleh, R.,Jackson, T.,King, A.,Lea, S.,Newman, J.,Rowlands, D.,Stuart, D.
Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity.
Structure, 4:135-145, 1996

PubMed Abstract: Foot-and-mouth disease virus (FMDV) is an extremely infectious and antigenically diverse picornavirus of cloven-hoofed animals. Strains of the A22 subtype have been reported to change antigenically when adapted to different growth conditions. To investigate the structural basis of this phenomenon we have determined the structures of two variants of an A22 virus.

PubMed: 8805520

実験手法

X-RAY DIFFRACTION (3 Å)