4GFY

Design of peptide inhibitors of phospholipase A2: crystal Structure of phospholipase A2 complexed with a designed tetrapeptide Val - Ilu- Ala - Lys at 2.7 A resolution

Summary for 4GFY

• Entry DOI: 10.2210/pdb4gfy/pdb
• Related: 4FGA
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, VIAK, SULFATE ION, ... (4 entities in total)
• Functional Keywords: pla2, anti-inflammatory, anti-coagulant, peptide-inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Daboia russellii pulchella (Russell's viper); More
• Total number of polymer chains: 2
• Total formula weight: 14156.39

Authors

Shukla, P.K.,Sinha, M.,Dey, S.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2012-08-04, release date: 2012-08-22, Last modification date: 2023-11-08)

• Primary citation: Shukla, P.K.,Sinha, M.,Dey, S.,Kaur, P.,Sharma, S.,Singh, T.P.; Design of peptide inhibitors of phospholipase A2: crystal Structure of phospholipase A2 complexed with a designed tetrapeptide Val - Ilu- Ala - Lys at 2.7 A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)