4PVS
Crystal structure of fully-cleaved human l-asparaginase protein in complex with l-aspartate
Replaces: 4GDWSummary for 4PVS
Entry DOI | 10.2210/pdb4pvs/pdb |
Related | 4PVP 4PVQ 4PVR |
Descriptor | Isoaspartyl peptidase/L-asparaginase, SODIUM ION, ASPARTIC ACID, ... (4 entities in total) |
Functional Keywords | ntn enzyme, homodimer, hydrolase, l-asparagine |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q7L266 |
Total number of polymer chains | 2 |
Total formula weight | 64891.56 |
Authors | |
Primary citation | Nomme, J.,Su, Y.,Konrad, M.,Lavie, A. Structures of apo and product-bound human L-asparaginase: insights into the mechanism of autoproteolysis and substrate hydrolysis. Biochemistry, 51:6816-6826, 2012 Cited by PubMed: 22861376DOI: 10.1021/bi300870g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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