4GDK
Crystal Structure of Human Atg12~Atg5 Conjugate in Complex with an N-terminal Fragment of Atg16L1
Summary for 4GDK
Entry DOI | 10.2210/pdb4gdk/pdb |
Related | 4GDL |
Descriptor | Ubiquitin-like protein ATG12, Autophagy protein 5, Autophagy-related protein 16-1, ... (5 entities in total) |
Functional Keywords | protein-protein conjugate, protein-protein complex, ubiquitin-like protein, autophagy, e3 ligase, ubiquitin-like fold, structural protein, isopeptide bond, cytoplasm and autophagosomal membranes, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : O94817 Q9H1Y0 Q676U5 |
Total number of polymer chains | 6 |
Total formula weight | 94903.30 |
Authors | Otomo, C.,Metlagel, Z.,Takaesu, G.,Otomo, T. (deposition date: 2012-07-31, release date: 2012-12-05, Last modification date: 2017-11-15) |
Primary citation | Otomo, C.,Metlagel, Z.,Takaesu, G.,Otomo, T. Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy. Nat.Struct.Mol.Biol., 20:59-66, 2013 Cited by PubMed: 23202584DOI: 10.1038/nsmb.2431 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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