4GD4

Crystal Structure of JMJD2A Complexed with Inhibitor

4GD4 の概要

• エントリーDOI: 10.2210/pdb4gd4/pdb
• 分子名称: Lysine-specific demethylase 4A, NICKEL (II) ION, ZINC ION, ... (6 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, oxidoreductase, jmjc domain, chromatin regulator, dioxygenase, transcription, demethylation, iron, 2-oxoglutarate, alpha-ketoglutarate, nucleus, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : O75164
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 89420.90

構造登録者

King, O.N.F.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,McDonough, M.A.,Schofield, C.J.,Structural Genomics Consortium (SGC) (登録日: 2012-07-31, 公開日: 2012-08-15, 最終更新日: 2024-02-28)

• 主引用文献: King, O.N.F.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,McDonough, M.A.,Schofield, C.J.,Structural Genomics Consortium (SGC); Crystal Structure of JMJD2A Complexed with Inhibitor; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (2.33 Å)