4GAA

Structure of Leukotriene A4 hydrolase from Xenopus laevis complexed with inhibitor bestatin

4GAA の概要

• エントリーDOI: 10.2210/pdb4gaa/pdb
• 分子名称: MGC78867 protein, ZINC ION, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ... (4 entities in total)
• 機能のキーワード: leukotriene a4 hydrolase, metalloprotein, hydrolase, protease, zinc binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Xenopus laevis (clawed frog,common platanna,platanna)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 138945.66

構造登録者

Stsiapanava, A.,Kumar, R.B.,Haeggstrom, J.Z.,Rinaldo-Matthis, A. (登録日: 2012-07-25, 公開日: 2013-06-12, 最終更新日: 2024-02-28)

• 主引用文献: Stsiapanava, A.,Tholander, F.,Kumar, R.B.,Qureshi, A.A.,Niegowski, D.,Hasan, M.,Thunnissen, M.,Haeggstrom, J.Z.,Rinaldo-Matthis, A.; Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.; Biochim.Biophys.Acta, 1844:439-446, 2014; PubMed: 24333438; DOI: 10.1016/j.bbapap.2013.12.003

実験手法

X-RAY DIFFRACTION (2.26 Å)