4G84

Crystal structure of human HisRS

Summary for 4G84

• Entry DOI: 10.2210/pdb4g84/pdb
• Related: 4G85
• Descriptor: Histidine--tRNA ligase, cytoplasmic, IMIDAZOLE, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: synthetase, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P12081
• Total number of polymer chains: 2
• Total formula weight: 105255.58

Authors

Wei, Z.,Wu, J.,Zhou, J.J.,Yang, X.-L.,Zhang, M.,Schimmel, P. (deposition date: 2012-07-21, release date: 2012-09-26, Last modification date: 2023-09-13)

• Primary citation: Xu, Z.,Wei, Z.,Zhou, J.J.,Ye, F.,Lo, W.S.,Wang, F.,Lau, C.F.,Wu, J.,Nangle, L.A.,Chiang, K.P.,Yang, X.L.,Zhang, M.,Schimmel, P.; Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.; Structure, 20:1470-1477, 2012; PubMed: 22958643; DOI: 10.1016/j.str.2012.08.001

Experimental method

X-RAY DIFFRACTION (2.4 Å)