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4G1C

Human SIRT5 bound to Succ-IDH2 and Carba-NAD

Summary for 4G1C
Entry DOI10.2210/pdb4g1c/pdb
Related4FVT
DescriptorNAD-dependent protein deacylase sirtuin-5, mitochondrial, Succinylated IDH2 peptide, ZINC ION, ... (5 entities in total)
Functional Keywordssirtuin, succinylated peptide, carbanad, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationMitochondrion matrix. Isoform 1: Cytoplasm. Isoform 2: Mitochondrion: Q9NXA8
Total number of polymer chains4
Total formula weight60130.99
Authors
Dai, H. (deposition date: 2012-07-10, release date: 2012-08-15, Last modification date: 2012-09-19)
Primary citationSzczepankiewicz, B.G.,Dai, H.,Koppetsch, K.J.,Qian, D.,Jiang, F.,Mao, C.,Perni, R.B.
Synthesis of Carba-NAD and the Structures of Its Ternary Complexes with SIRT3 and SIRT5.
J.Org.Chem., 77:7319-7329, 2012
Cited by
PubMed: 22849721
DOI: 10.1021/jo301067e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.944 Å)
Structure validation

217705

數據於2024-03-27公開中

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