4FXM

Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P21212)

Summary for 4FXM

• Entry DOI: 10.2210/pdb4fxm/pdb
• Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION, N-METHYLMESOPORPHYRIN, ... (4 entities in total)
• Functional Keywords: parallel quadruplex, n-methyl mesoporphyrin ix, dna
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 7681.51

Authors

Nicoludis, J.M.,Miller, S.T.,Jeffrey, P.,Lawton, T.J.,Rosenzweig, A.C.,Yatsunyk, L.A. (deposition date: 2012-07-03, release date: 2012-12-26, Last modification date: 2023-09-13)

• Primary citation: Nicoludis, J.M.,Miller, S.T.,Jeffrey, P.D.,Barrett, S.P.,Rablen, P.R.,Lawton, T.J.,Yatsunyk, L.A.; Optimized End-Stacking Provides Specificity of N-Methyl Mesoporphyrin IX for Human Telomeric G-Quadruplex DNA.; J.Am.Chem.Soc., 134:20446-20456, 2012; PubMed: 23181361; DOI: 10.1021/ja3088746

Experimental method

X-RAY DIFFRACTION (1.651 Å)