4FX4

Crystal structure of M. tuberculosis transcriptional regulator MOSR (Rv1049) in compex with DNA

Summary for 4FX4

• Entry DOI: 10.2210/pdb4fx4/pdb
• Related: 4FX0
• Descriptor: DNA (5'-D(*TP*AP*CP*AP*GP*AP*TP*TP*CP*GP*TP*GP*TP*AP*GP*CP*TP*AP*CP*AP*CP*GP*AP*AP*TP*CP*TP*GP*T)-3'), PROBABLE TRANSCRIPTIONAL REPRESSOR PROTEIN, PHOSPHATE ION (3 entities in total)
• Functional Keywords: helix-turn-helix, transcriptional repressor, dna binding, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 4
• Total formula weight: 50598.87

Authors

Brugarolas, P.,He, C. (deposition date: 2012-07-02, release date: 2012-09-26, Last modification date: 2023-12-06)

• Primary citation: Brugarolas, P.,Movahedzadeh, F.,Wang, Y.,Zhang, N.,Bartek, I.L.,Gao, Y.N.,Voskuil, M.I.,Franzblau, S.G.,He, C.; The Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosis.; J.Biol.Chem., 287:37703-37712, 2012; PubMed: 22992749; DOI: 10.1074/jbc.M112.388611

Experimental method

X-RAY DIFFRACTION (3.1001 Å)