4FTV
The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide
Summary for 4FTV
Entry DOI | 10.2210/pdb4ftv/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Protein Tax-1, ... (7 entities in total) |
Functional Keywords | tax peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, high affinity, c134, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 Host nucleus (By similarity): P0C213 |
Total number of polymer chains | 5 |
Total formula weight | 95249.41 |
Authors | |
Primary citation | Borbulevych, O.Y.,Baker, B.M. Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity To be Published, |
Experimental method | X-RAY DIFFRACTION (2.74 Å) |
Structure validation
Download full validation report