4FTV

The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide

4FTV の概要

• エントリーDOI: 10.2210/pdb4ftv/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Protein Tax-1, ... (7 entities in total)
• 機能のキーワード: tax peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, high affinity, c134, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769; Host nucleus (By similarity): P0C213
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 95249.41

構造登録者

Borbulevych, O.Y.,Baker, B.M. (登録日: 2012-06-28, 公開日: 2013-07-03)

• 主引用文献: Borbulevych, O.Y.,Baker, B.M.; Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity; To be Published,

実験手法

X-RAY DIFFRACTION (2.74 Å)