4FR6

tRNA-Guanine Transglycosylase cocrystallized with pyridyl-alkine-substituted lin-benzoguanine ligand

4FR6 の概要

• エントリーDOI: 10.2210/pdb4fr6/pdb
• 関連するPDBエントリー: 3EOS 3S1G 3V0Y 4FPS 4FR1 4FSA
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-(methylamino)-4-[2-({[trans-4-(pyridin-3-ylethynyl)cyclohexyl]methyl}amino)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• 機能のキーワード: tim barrel, glycosyltransferase, queuosine, biosynthesis, transferase, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Zymomonas mobilis subsp. mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43461.68

構造登録者

Immekus, F.,Klebe, G. (登録日: 2012-06-26, 公開日: 2013-07-24, 最終更新日: 2023-09-13)

• 主引用文献: Immekus, F.,Barandun, L.J.,Betz, M.,Debaene, F.,Petiot, S.,Sanglier-Cianferani, S.,Diederich, F.,Klebe, G.; Studies on TGT homodimer interface; To be Published,

実験手法

X-RAY DIFFRACTION (1.59 Å)