4FR1
tRNA-Guanine Transglycosylase cocrystallized with alkine-substituted lin-benzoguanine ligand
Summary for 4FR1
Entry DOI | 10.2210/pdb4fr1/pdb |
Related | 3EOS 3S1G 3V0Y 4FPS 4FR6 4FSA |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-4-[2-({[trans-4-(biphenyl-4-ylethynyl)cyclohexyl]methyl}amino)ethyl]-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total) |
Functional Keywords | tim barrel, glycosyltransferase, queuosine, biosynthesis, transferase, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43536.79 |
Authors | Immekus, F.,Klebe, G. (deposition date: 2012-06-26, release date: 2013-07-24, Last modification date: 2023-09-13) |
Primary citation | Immekus, F.,Barandun, L.J.,Betz, M.,Debaene, F.,Petiot, S.,Sanglier-Cianferani, S.,Diederich, F.,Klebe, G. Studies on TGT homodimer interface To be Published, |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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