4FQW
Crystal Structure of AAAA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant
Summary for 4FQW
Entry DOI | 10.2210/pdb4fqw/pdb |
Related | 4FRA 4FRB 4FRD 4FRE 4FRH 4FRL 4FRM 4FRO 4FRP 4FRQ |
Descriptor | Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, beta-D-galactopyranose, ... (5 entities in total) |
Functional Keywords | manganese, abo rossmann fold, retaining glycosyltransferase, glycoprotein, blood group antigen, metal binding, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442 |
Total number of polymer chains | 1 |
Total formula weight | 34954.98 |
Authors | Johal, A.R.,Alfaro, J.A.,Blackler, R.J.,Schuman, B.,Borisova, S.N.,Evans, S.V. (deposition date: 2012-06-25, release date: 2013-12-25, Last modification date: 2023-09-13) |
Primary citation | Johal, A.R.,Blackler, R.J.,Alfaro, J.A.,Schuman, B.,Borisova, S.,Evans, S.V. pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24:237-246, 2014 Cited by PubMed: 24265507DOI: 10.1093/glycob/cwt098 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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