4FQ9

Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa

Summary for 4FQ9

Entry DOI	10.2210/pdb4fq9/pdb
Descriptor	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	lyase, hot dog fold, fatty acid biosynthesis, bacterial virulence
Biological source	Pseudomonas aeruginosa
Cellular location	Cytoplasm (By similarity): O33877
Total number of polymer chains	10
Total formula weight	190310.70
Authors	Moynie, L.,Mcmahon, S.A.,Duthie, F.G.,Naismith, J.H. (deposition date: 2012-06-25, release date: 2013-03-27, Last modification date: 2024-02-28)
Primary citation	Moynie, L.,Leckie, S.M.,McMahon, S.A.,Duthie, F.G.,Koehnke, A.,Taylor, J.W.,Alphey, M.S.,Brenk, R.,Smith, A.D.,Naismith, J.H. Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa J.Mol.Biol., 425:365-377, 2013 Cited by PubMed: 23174186 DOI: 10.1016/j.jmb.2012.11.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation