4FNS

Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin

Summary for 4FNS

• Entry DOI: 10.2210/pdb4fns/pdb
• Related: 4FNP 4FNQ 4FNR 4FNT 4FNU
• Descriptor: Alpha-galactosidase AgaA, (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, SULFATE ION, ... (5 entities in total)
• Functional Keywords: glycoside hydrolase, hydrolase
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 4
• Total formula weight: 334682.70

Authors

Merceron, R.,Foucault, M.,Haser, R.,Mattes, R.,Watzlawick, H.,Gouet, P. (deposition date: 2012-06-20, release date: 2012-10-03, Last modification date: 2023-09-13)

• Primary citation: Merceron, R.,Foucault, M.,Haser, R.,Mattes, R.,Watzlawick, H.,Gouet, P.; The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies; J.Biol.Chem., 287:39642-39652, 2012; PubMed: 23012371; DOI: 10.1074/jbc.M112.394114

Experimental method

X-RAY DIFFRACTION (2.6 Å)