4FH0

Crystal Structure of Human BinCARD CARD, double mutant F16M/L66M SeMet form

Summary for 4FH0

• Entry DOI: 10.2210/pdb4fh0/pdb
• Related: 4DWN
• Descriptor: Bcl10-interacting CARD protein, SULFATE ION (3 entities in total)
• Functional Keywords: immune system, apoptosis, mainly alpha, bcl10, nucleus, er, mitochondria
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Nucleus . Isoform 2: Endoplasmic reticulum membrane ; Single-pass membrane protein : Q96LW7
• Total number of polymer chains: 2
• Total formula weight: 24559.17

Authors

Chen, K.-E.,Kobe, B.,Martin, J.L. (deposition date: 2012-06-05, release date: 2013-02-06, Last modification date: 2018-01-24)

• Primary citation: Chen, K.E.,Richards, A.A.,Caradoc-Davies, T.T.,Vajjhala, P.R.,Robin, G.,Lua, L.H.,Hill, J.M.,Schroder, K.,Sweet, M.J.,Kellie, S.,Kobe, B.,Martin, J.; The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.; Acta Crystallogr.,Sect.D, 69:774-784, 2013; PubMed: 23633586; DOI: 10.1107/S0907444913001558

Experimental method

X-RAY DIFFRACTION (1.4 Å)