4FFY

Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007.

4FFY の概要

• エントリーDOI: 10.2210/pdb4ffy/pdb
• 関連するPDBエントリー: 3IRC 4FFZ
• 分子名称: DENV1-E111 single chain variable fragment (light chain), DENV1-E111 single chain variable fragment (heavy chain), envelope glycoprotein, ... (7 entities in total)
• 機能のキーワード: viral envelope proteins, structural genomics, antibody epitopes, flavivirus, dengue virus, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, immune system, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Mus musculus; 詳細
• 細胞内の位置: Envelope protein E: Virion membrane; Multi- pass membrane protein: Q9J7C6
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 40230.40

構造登録者

Austin, S.K.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2012-06-01, 公開日: 2012-06-20, 最終更新日: 2012-10-31)

• 主引用文献: Austin, S.K.,Dowd, K.A.,Shrestha, B.,Nelson, C.A.,Edeling, M.A.,Johnson, S.,Pierson, T.C.,Diamond, M.S.,Fremont, D.H.; Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.; Plos Pathog., 8:e1002930-e1002930, 2012; PubMed: 23055922; DOI: 10.1371/journal.ppat.1002930

実験手法

X-RAY DIFFRACTION (2.5 Å)