4FDL

Crystal structure of Caspase-7

Summary for 4FDL

Entry DOI	10.2210/pdb4fdl/pdb
Related	4FEA
Descriptor	Caspase-7 (2 entities in total)
Functional Keywords	cysteine protease, central cavity, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P55210
Total number of polymer chains	2
Total formula weight	69132.20
Authors	Kabaleeswaran, V. (deposition date: 2012-05-28, release date: 2012-08-01, Last modification date: 2023-09-13)
Primary citation	Feldman, T.,Kabaleeswaran, V.,Jang, S.B.,Antczak, C.,Djaballah, H.,Wu, H.,Jiang, X. A class of allosteric caspase inhibitors identified by high-throughput screening. Mol.Cell, 47:585-595, 2012 Cited by PubMed: 22795132 DOI: 10.1016/j.molcel.2012.06.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.801 Å)

Structure validation