4FBX
Complex structure of human protein kinase CK2 catalytic subunit crystallized in the presence of a bisubstrate inhibitor
Summary for 4FBX
Entry DOI | 10.2210/pdb4fbx/pdb |
Related | 1JWH 1LP4 3BQC 3NSZ 3OFM |
Related PRD ID | PRD_000870 |
Descriptor | Casein kinase II subunit alpha, bisubstrate inhibitor, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | protein kinase fold, protein phosphorylation, bisubstrate inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 41481.41 |
Authors | Enkvist, E.,Viht, K.,Bischoff, N.,Vahter, J.,Saaver, S.,Raidaru, G.,Issinger, O.-G.,Niefind, K.,Uri, A. (deposition date: 2012-05-23, release date: 2012-10-17, Last modification date: 2024-07-10) |
Primary citation | Enkvist, E.,Viht, K.,Bischoff, N.,Vahter, J.,Saaver, S.,Raidaru, G.,Issinger, O.G.,Niefind, K.,Uri, A. A subnanomolar fluorescent probe for protein kinase CK2 interaction studies. Org.Biomol.Chem., 10:8645-8653, 2012 Cited by PubMed: 23032938DOI: 10.1039/c2ob26022k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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