4F83

Crystal structure of the receptor binding domain of botulinum neurotoxin mosaic serotype C/D with a tetraethylene glycol molecule bound on the Hcn sub-domain and a sulfate ion at the putative active site

4F83 の概要

• エントリーDOI: 10.2210/pdb4f83/pdb
• 分子名称: Type C neurotoxin, TETRAETHYLENE GLYCOL, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, botulinum neurotoxin, mosaic serotype c/d, toxin
• 由来する生物種: Clostridium botulinum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50172.41

構造登録者

Zhang, Y.,Buchko, G.W.,Gardberg, A.,Edwards, T.E.,Sankaran, B.,Robinson, H.,Varnum, S.M.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-05-16, 公開日: 2012-06-20, 最終更新日: 2013-06-12)

• 主引用文献: Zhang, Y.,Gardberg, A.S.,Edwards, T.E.,Sankaran, B.,Robinson, H.,Varnum, S.M.,Buchko, G.W.; Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D.; Biochimie, 95:1379-1385, 2013; PubMed: 23523511; DOI: 10.1016/j.biochi.2013.03.006

実験手法

X-RAY DIFFRACTION (1.7 Å)