4F7I

Structure of Isopropylmalate dehydrogenase from Thermus thermophilus in complex with IPM, Mn and NADH

Summary for 4F7I

• Entry DOI: 10.2210/pdb4f7i/pdb
• Related: 1HEX 2Y3Z 2Y40 2Y41 2Y42 2ZTW
• Descriptor: 3-isopropylmalate dehydrogenase, 3-ISOPROPYLMALIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (9 entities in total)
• Functional Keywords: isopropylmalate dehydrogenase, 3-ipm-dh, beta-ipm dehydrogenase, imdh, ipmdh, oxidoreductase
• Biological source: Thermus thermophilus
• Total number of polymer chains: 4
• Total formula weight: 161022.26

Authors

Pallo, A.,Graczer, E.,Zavodszky, P.,Weiss, M.S.,Vas, M. (deposition date: 2012-05-16, release date: 2012-06-13, Last modification date: 2023-09-13)

• Primary citation: Pallo, A.,Olah, J.,Graczer, E.,Merli, A.,Zavodszky, P.,Weiss, M.S.,Vas, M.; Structural and energetic basis of isopropylmalate dehydrogenase enzyme catalysis.; Febs J., 281:5063-5076, 2014; PubMed: 25211160; DOI: 10.1111/febs.13044

Experimental method

X-RAY DIFFRACTION (2 Å)